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Dual Blade Cutter

Biomaterials Testing with the SER

The characterization of the physical properties of biomaterials such as biological soft and connective tissues inherently requires the testing of such materials within a simulated body fluid environment. Because both of the detachable drums are cantilevered and suspended from the SER3 base chassis, the SER3 models that are configured for use on controlled stress/strain rotational rheometers such as the SER3-P, SER3-G, SER3-T, and SER3-M are capable of fluid immersion testing. The drums of said SER3 models can be raised from and lowered into a controlled temperature fluid environment contained within a jacketed beaker or other such fluid containment vessel for the purposes of characterizing the physical properties of natural or synthetic biomaterials. In this manner, sample specimens can be easily loaded and unloaded from the windup drums while the SER3 is completely raised from the fluid surface. The image below depicts a SER Universal Testing Platform hosted on an Anton Paar MCR host rotational rheometer suspended above a controlled temperature fluid environment contained within a glass jacketed beaker.

Fluid Immersion Testing Setup

Pig Artery Diagram Pig Artery Ring Section

The following videos depict the tensile testing of a ring-shaped cross-sectional blood vessel specimen dissected from a porcine right sublcavian artery as illustrated in the above diagram and photo. The ring specimens were simply looped around the securing clamps before clamp insertion into the windup drums thereby defining a ring tensile test which is commonly used for evaluating hoop stresses in pipes and other such pressure conduits. Note as well that all of the following videos depict rough textured SER3-DR drums that were used in order to assist in sample gripping during the stretching process within the fluid environment.
Note that for all of the SER videoclips depicted below, the sample deformation remains in a fixed plane and is ALWAYS clearly and easily accessible for deformation visualization.

Also note how in all cases only the drums of the SER need to be immersed within the fluid environment.

Tensile Fluid Immersion Testing with Artery Tissue

SER Drums Fluid Immersion Immersion of the SER Drums This video depicts the immersion process of the SER drums into a simulated biological fluid environment held at a controlled temperature of 37C. Also shown is an arterial specimen loaded on the rough textured SER drums. Note how only the drums of the SER are immersed within the fluid.
(AVI file format: 1.90 MB)
Subclavian Artery at 0.1s-1 Arterial Section at 0.1s-1 This video depicts the uniaxial extensional deformation of an arterial ring section (tunica externa + media + intima) at 37C being stretched at a Hencky strain rate of 0.1 s-1. Note how the fibrous tunica externa layer ruptures prior to the rupture of the more muscular tunica media layer.
(AVI file format: 0.37 MB)
Subclavian Artery at 1s-1 Arterial Section at 1s-1 This video depicts the uniaxial extensional deformation of an arterial ring section (tunica externa + media + intima) at 37C being stretched at a Hencky strain rate of 1 s-1.
(AVI file format: 0.26 MB)
Tunica externa at 0.1s-1 Tunica externa at 0.1s-1 This video depicts the uniaxial extensional deformation of the very thin, fibrous tunica externa layer extracted from an arterial ring section being stretched at a Hencky strain rate of 0.1 s-1 at 37C.
(AVI file format: 0.69 MB)
Tunica media at 0.1s-1 Tunica media at 0.1s-1 This video depicts the uniaxial extensional deformation of the thick, muscular tunica media layer extracted from an arterial ring section being stretched at a Hencky strain rate of 0.1 s-1 at 37C.
(AVI file format: 0.75 MB)

The SER Advantage

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